Modified Kidney Sodium Potassium Adenosine-Triphosphatase Kinetics in Protein Energy Malnutrition
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چکیده
منابع مشابه
Activation by adenosine triphosphate in the phosphorylation kinetics of sodium and potassium ion transport adenosine triphosphatase.
The steady state kinetics of sodium and potassium ion transport adenosine triphosphatase (EC 3.6-l. 3) suggests an activating action of adenosine triphosphate in addition to its action as a phosphate donor. This action might be an acceleration of dissociation of Kf or its congeners from the enzyme. To test this possibility transient kinetics of the phosphoenzyme was investigated. In membranes f...
متن کاملDistribution of lens sodium-potassium-adenosine triphosphatase.
PURPOSE The specific activity of sodium-potassium-adenosine triphosphatase (Na-K-ATPase) in lens fiber cells is lower than the specific activity in lens epithelium. To test whether there is a reduction in the expression of Na-K-ATPase molecules in lens fibers, a Western blot technique was used. METHODS Membrane material was isolated from different regions of the rabbit lens. Na-K-ATPase (aden...
متن کاملThe role of sodium-potassium-activated adenosine triphosphatase in the reabsorption of sodium by the kidney.
In order to evaluate the possible role of sodium- and potassium-activated adenosine triphosphatase in the active transport of sodium by the renal tubules, we examined the effect of large changes in the tubular reabsorptive load of sodium on the Na-K-ATPase activity of rat kidney homogenates. Glomerular filtration and tubular reabsorption of sodium per gram of kidney tissue increased progressive...
متن کاملRenal sodium-potassium-activated adenosine triphosphatase and sodium reabsorption.
The role of renal Na(+),K(+)-ATPase in sodium reabsorption was further examined in dogs in which digoxin, a specific inhibitor of the enzyme system, was infused into one renal artery in doses ranging from 0.4 to 0.9 mug/kg/min (low dose) and from 1.0 to 4.0 mug/kg/min (high dose). A significant natriuresis occurred with both dose ranges which was accompanied by inhibition of Na(+),K(+)-ATPase o...
متن کاملEffects of three sodium-potassium adenosine triphosphatase inhibitors.
Reports from several laboratories suggest the presence of an ouabainlike compound in plasma and various animal tissues, particularly during acute volume expansion and in low-renin hypertension. It has been hypothesized that this compound, through inhibition of the Na(+)-K+ pump, can constrict blood vessels, enhance vasoconstriction in response to agonists, increase cardiac contractility, raise ...
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 1986
ISSN: 1880-5086,0912-0009
DOI: 10.3164/jcbn.1.229